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Statistical Models for Prognostication
Author Bio
Introduction
Predictions: Statistical Models
Insight: Statistical Models
Ingredients: Statistical Models
Theoretical Aspects
Central Concepts
Currently selected section: Regression Models
Problems: Regression
Practical Advice
Example 1
Example 2
Chapter 8: Statistical Models for Prognostication: Development of Regression Models
        

Presentation of Predictive Models

The presentation of a predictive model is important if we aim for practical application of the model in clinical situations. Presentation of a regression formula, or a table with regression coefficients, may be useful to obtain insight into the prognostic effect of the predictors included in the model, but fails to readily provide the clinician with a predicted probability (Harrell et al., 1996).

Predicted probabilities can more easily be derived from a regression model when presented in another format, as detailed below.

Table 7.2: Presentation Formats
Score Chart
Scores based on regression coefficients (multiplication by 10 and rounding). Scores corresponding to patient’s predictor values added in a sumscore.
For linear models, sumscore is predicted value. For generalized linear models, the sumscore is similar to the linear predictor. For logistic regression models, the sumscore is translated back to a probability through the logistic transformation.
Survival probabilities at a certain follow-up time can be estimated based on a predictive survival model.

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Nomogram
The effects of predictors are shown graphically and the predicted value can be read directly.Click for Example
Table
Sometimes, a table can be created which shows the predictions according to all combinations of the values of the predictors. When only categorical predictors are considered, the original model can be shown. When continuous predictors are considered, these need to be
categorized for presentation in a table.
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Metamodel
A recent approach is to develop a model that predicts the predictions from the original model (Harrell et al., 1998). Such a meta-model can be simpler in structure
than the original model, while predictive performance is not hampered much. 
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