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Ewout
Steyerberg received his PhD from the Medical Faculty at
Erasmus University Rotterdam, the Netherlands, in 1996,
and in 1997 became registered as an Epidemiologist. Since
1991 he has worked as a scientific researcher at the Center
for Clinical Decision Sciences, Department of Public Health,
Erasmus University, Rotterdam. He has been a staff member
of the Consultation Center for Patient-related Research
(CPO), concentrating in methodological consultations from
the Academic Hospital, Rotterdam, since 1994. He is a member
of the Society for Medical Decision Making, the International
Society for Clinical Biostatistics, and the Netherlands
Epidemiological Society. In 1999 he received a fellowship
from the Royal Netherlands Academy for Arts and Sciences.
His special research interest is in the development, validation,
and updating of prognostic models, where advanced statistical
methods are applied. Clinical examples include oncology,
cardiovascular disease, tropical medicine, pediatrics, and
internal medicine.
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Frank
E. Harrell, Jr. received his PhD from the University of
North Carolina, Chapel Hill in Biostatistics in 1979. He
was a faculty member in the Division of Biometry at the
Duke University Medical Center for over 17 years before
founding a new Division of Biostatistics and Epidemiology
at the University of Virginia in 1996. He served on the
FDA Cardio-Renal Advisory Committee from 1987-1991, as a
FDA Expert Statistical Consultant in Biometrics from 1992
to the present and as the Co-editor of Health Services and
Outcomes Research Methodology from 1999 to the present.
He has served on Safety and Data Monitoring and Steering
Committees for heart failure, anti-platelet aggregation,
and artificial liver trials. His research interests are
in the areas of statistical modeling and model variation,
statistical computation and graphics, clinical trials, health
services and outcomes research, medical diagnostic and prognostic
models, bootstrapping, and Bayesian inference.
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