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Within-patient studies: Cross-over and n-of-1
Author Bio Introduction Carry-over Problem
Currently selected section: Test for Carry-over?
AB/BA Analysis
n-of-1 Trials
Conclusions




Chapter 6: Within-patient studies: Cross-over Trials and n-of-1 Studies: Can we test for carry-over?
        

If we form totals over both periods for the patients in an AB/BA design, these totals reflect the effect of both periods and both treatments. They thus cannot differ between patients in any way that reflects these effects. However, if there is carry-over, the order in which treatments are given will affect these totals. We may thus compare the totals between sequences to form a test of carry-over.

Question 3.1

How does the power of the test for carry-over compare to the test for the treatment effect?

Selection ASame
Selection BLower
Selection CHigher

 

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