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Clinical Research: Constipation Sections
Author Biography
Introduction
Currently Selected Section: What is constipation?
Understanding the problem
Objective Measurement
Subjective Measurement
Measuring Components
Precipitating Factors
Therapeutic Comparisons
Research Questions
Conclusion




Chapter 3: Methods for Clinical Research in Constipation: What is Constipation?
 

Despite the Rome criteria, people have their own personal definition of what it means to be constipated. It is useful to compare and contrast the components of the Rome criteria with the views of various patient populations.

Click on patients’ definitions of constipation
to compare with "Rome criteria."
Hospice patients (Sykes, unpublished observations)
Family practice patients (Herz et al., 1996)
"Constipated" patients (Ashraf et al., 1996)


Constipation and time requirements

The Rome criteria were intended to clarify the diagnosis of functional constipation in an essentially healthy population. When constipation is an accompaniment of illness, the time requirement, in particular, becomes less appropriate. No other symptom is approached in this way: relief is not offered for pain or breathlessness only after it has been endured for at least three months. In addition to the unnecessary suffering that this would cause, this period would be a substantial fraction of the life expectancy of many palliative care patients.

Hence an approach to the definition of constipation that is appropriate in a gastroenterology clinic results in denying the existence of constipation in most palliative care patients, even though constipation has been found to be a greater cause of distress than pain in this group (Holmes, 1989). The key is the identity of constipation as a symptom, whose presence or absence is defined by the patient, not the doctor.

Thus, while a proposed definition of constipation in palliative care is "the passage of small hard feces infrequently and with difficulty", it is for the patient to define how infrequently and with how much difficulty. Indeed, there are other still more subjective sensations that together suggest to the individual that they are constipated and which are even harder to capture in any tight, quantitative definition for research purposes. We may wish to measure bowel movement frequency and other parameters of intestinal function that can be expressed numerically, but alongside them must be included a measure which allows patients to express the extent to which they perceive themselves to be constipated (see Subjective Measurement of Constipation).


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