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Temporomandibular Disorders
Author Bios
Introduction
Epidemiology
Currently selected section: Population Perspective
Developmental Perspective
Ecological Perspective
Epidemiologic Measures
Defining a Case
Pain Location
Pain Frequency, Duration and Severity
Recency of Pain
Ambient Pain or Pain on Function?
Clinical Signs and Symptoms
Pain Impact/Disability
Currently selected section: Co-morbidity
Choosing an Appropriate Design
Cross-sectional Surveys
Longitudinal Studies
Case-control Studies
Prospective Designs
Preventive and Clinical Trials
Clinical Epidemiology
Practical Considerations
Sample Size
Standardizing Data Collection
Response Burden
Summary

 

Chapter 26: Studying the Epidemiology of Temporomanibular Disorders: Co-morbidity
        

In epidemiologic studies examining natural history or risk factors for TMD, the question arises as to whether cases with a co-morbid pain condition be included or excluded from the study. Since epidemiologists have generally studied conditions that are relatively rare compared to pain conditions, they have often opted for exclusion of persons with co-morbid conditions.

However, a significant percentage of people with TMD pain have other chronic pain conditions. Some of this co-morbidity may occur simply because a number of pain conditions--notably headache and back pain-- are very prevalent and would be expected to occur at high rates among people with TMD, just as in the general population.

Headache, in particular, is frequently co-morbid with TMD pain. However, rates of severe headache appear to be higher in persons with TMD than in the population as a whole. Possibly headache and TMD share common risk factors, or possibly they represent a spectrum of related conditions (Benoliel and Sharav, 1998).

In addition, some individuals may be predisposed to experience pain in multiple body sites. There is considerable evidence that persons with TMD who have multiple additional pains are more psychologically distressed (LeResche et al., 1987; Dworkin et al., 1990b), and at risk for poorer long-term outcomes of their TMD pain (John et al., 2003).

Thus, excluding persons with other pain conditions from studies of TMD pain is unlikely to be a satisfactory solution. It may, however, be necessary to differentiate "pure" cases of TMD pain from those with co-morbid pain conditions.

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