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Neural Mechanisms of Cardiac Pain
Author Biography
Currently selected section: Introduction
Anterolateral System
Somatic vs. Visceral Nociceptive Processing
Angina Pectoris
Sympathetic Sensory Innervation
Referred Pain
Vagal Sensory Innervation
Other Ascending Pathways
Central Sensitization
Thalamus and Cerebral Cortex
Neurophysiology of Angina Pectorsis
Nausea and Vomiting

Dyspnea
Summary


Chapter 25:Neural Mechanisms of Cardiac Pain: Introduction
        

While cleaning up the stove after cooking a meal, you inadvertently touch a burner that is still hot. You immediately withdraw your hand from the hot burner, but you receive a mild burn on your little finger. You sense a sharp pain at first, which becomes a dull ache after an hour. Activation of which pathway lead to these sensations?

You Answered:

Selection CCuneate fasciculus

Incorrect

Pain is a subjective sensation that serves a protective role for the individual. For example, in the scenario above, you withdrew your hand from the stove to prevent being burned. Pain is subjective because people have different thresholds for pain, and even different cultures respond to potentially painful stimuli in different ways.

On the other hand, the sensory nerve fibers that ultimately result in pain operate similarly in all of us; that is, their thresholds for activation are similar in everyone. Hence the cerebral cortex determines whether a potentially painful stimulus (that is, a stimulus that excites nerve endings sensitive to tissue injury) will be interpreted as "pain."

Furthermore, the cortex ultimately determines the intensity of pain. Because of the individual variability in the interpretation of pain, coupled with the similarity in the responses of sensory neurons, we refer to neurons that are sensitive to stimuli that can evoke the sensation of pain as "nociceptive" neurons or simply "nociceptors".

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