| |
Compliance or adherence
to the study protocol should be actively encouraged throughout
the design and conduct of any trial. It is imperative that TMD
RCT compliance be viewed from two perspectives:
- For the patient,
there are issues relating to patient burden and patient compensation.
- For the clinician,
there is the need for adherence to treatment protocols.
A practical consideration
in planning RCTs using TMD clinical cases is the burden the trial
may place on the patient, above and beyond the burden of customary
treatment. In an RCT, which remains one of the more expensive
forms of clinical investigation, loss of subjects for any reason
is regrettable, but it is especially regrettable when the investigators
contribute to drop out rates by not being sensitive to the RCT
study patient burden.
|