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Anorexia Case Study Sections
Author Bio
Introduction
Commentator Bio
Protocol Schema
Protocol Background
Protocol Goals
Currently selected section: Patient Eligibility
Test Schedule
Stratification Factors
Registration/Randomization
Protocol Treatment
Dosage Modification
Ancillary Treatment
Toxicity Monitoring
Treatment Evaluation
Treatment/Follow-up
Ancillary Studies
Drug Information
Statistical Considerations
Pathology Considerations
Records/Data Collection Procedures
Budget
Appendices

 

Chapter 2A: Measuring Cancer Anorexia/Cachexia: A Case Study: Patient Eligibility
 

3.111 Adult (³age 18).

3.112 Histological or cytological proven cancer other than brain, breast, ovarian, or endometrial cancer. If the patient has multiple primaries or an unknown primary, the currently active cancer cannot be known to be of brain, breast, ovarian, or endometrial cancer. Microphone Image

3.113 Patient life expectancy ³3 months.

3.114 ECOG performance score 0, 1, or 2.

3.115 Able to reliably take oral medication.

3.116 Alert and mentally competent.Microphone Image

3.117 Patients must have a history of having lost at least five pounds (2.3 kg) in weight over the preceding two months or less (excluding perioperative weight loss; documented weight loss not required) and/or have estimated caloric intake of <20 cal/kg daily.

3.118 The attending physician must determine that weight gain would be beneficial to the patient.

3.119a Patient perceives weight loss as a problem. Microphone Image

3.119b Concurrent chemotherapy and/or radiotherapy is permitted.

3.119c All patients should be considered incurable with available therapies.

3.12 Contraindications. Microphone Image

3.121 Receiving tube feedings or parenteral nutrition.

3.122 Evidence of ascites.

3.123 Current (within the past month) or planned treatment with adrenal steroids (short-term use of dexamethasone around days of intravenous chemotherapy is allowed for protection against emesis), androgens, progestational agents, or appetite stimulants (e.g. dronabinol).

 

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