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Epidemiological Methods in Studies of Symptoms in Advanced Disease
Author Bios
Why Study Advanced Disease?
Why Epidemiology?
Currently selected selection: Incidence and Prevalence
Using Incidence and Prevalence
Definition of a Case
Defining Time, Place, Person
Types of Study Design
Cross-Sectional Studies
Longitudinal Studies
Measurement
Bias
Selection Bias
Measurement Bias
Presenting and Interpreting Results
Practical Example
Calculating Prevalence
Conclusion


Chapter 19: Epidemiological Methods in Studies of Symptoms in Advanced Disease: Incidence and Prevalence
         


The classic descriptors of how common a disease, symptom, or problem is in a population are incidence and prevalence.

Incidence quantifies the number of new problems that develop in a population at risk during a given period of time (for example, new symptoms such as new instances of breathlessness). Incidence is quantified as a RATE:

incidence=
number of new problems during a given period of time
total population (or person-time) at risk

Incidence provides an estimate of the probability (or risk) that a patient will develop the problem during the given period of time.

For example: At admission, 120 patients free from breathlessness are followed for 3 weeks. In this period of time, 45 developed breathlessness. This results in a incidence rate of 45 per 120 (or 37.5 %) during the 3 week period. This means that, at admission, each patient had a .375 probability to develop breathlessness during the next 3 weeks.

Prevalence quantifies the proportion of a given population with a problem (for example, breathlessness) at a designated time. When the term is used without qualification of a time period it is usually the point prevalence, for example the proportion of patients with breathlessness at a given point in time. Note that, although the term "prevalence rate" is used for prevalence, prevalence is a proportion, not a rate.

prevalence=
number of patients with the problemat a designed time
total population

For example: At admission, 150 patients were screened for the presence of breathlessness, and 30 resulted affected by the symptom. This results in a breathlessness prevalence at admission of 20% (30/150).

The period prevalence refers to the proportion of a given population with a problem (for example, breathlessness) at any time during a specified period. Period prevalence can refer to proportion with the problem at any time in one year (annual prevalence) or at any time in their life (lifetime prevalence).


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