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Epidemiological Methods in Studies of Symptoms in Advanced Disease
Author Bios
Why Study Advanced Disease?
Why Epidemiology?
Incidence and Prevalence
Using Incidence and Prevalence
Definition of a Case
Defining Time, Place, Person
Types of Study Design
Cross-Sectional Studies
Longitudinal Studies
Measurement
Bias
Selection Bias
Measurement Bias
Currently selected selection: Presenting and Interpreting Results
Practical Example
Calculating Prevalence
Conclusion


Chapter 19: Epidemiological Methods in Studies of Symptoms in Advanced Disease: Presenting and Interpreting Results
         


Wherever results are reported in a journal or scientific conference there are some general rules that should be followed to ensure clear and valid exposition of the results.

The results section of an article or presentation should follow the design of the study and its methods. First, it should contain all the results relevant to interpret the validity of the data. This is particularly important in studies of symptoms in advanced disease, and should acknowledge any potential sources of bias. Two components are critical: (1) the proportion of evaluated patients (the compliance rate), and (2) the proportion of patients who correctly followed the evaluation procedures (the adherence rate).

Problem 14.1

Suppose that you wish to examine the prevalence of severe breathlessness at admission in a consecutive series of 200 new cancer patients entering a palliative care program. Unfortunately, at the end of the study you have be able to evaluate only 120 patients out of the 200 planned. Twenty refused, 20 attended when you were off work with a bad cold, 30 were deemed by the palliative care nurse as being too ill for interview, and 10 died before you could interview them.

The prevalence of severe breathlessness among the 120 patients was 50%.

Question 14.1

Should you describe in detail the reasons for not evaluating severe breathlessness in all the patients you had planned?
Selection AYes
Selection BNo

Question 14.2

Do you think that the prevalence of severe breathlessness is likely to be the same in the group of patients who died as in the rest of the sample?
Selection AYes
Selection BNo

Question 14.3

Do you think that the prevalence of severe breathlessness is likely to be the same in the group of patients who were too ill to be interviewed as in the rest of the sample?
Selection AYes
Selection BNo

Question 14.4

Do you think that the prevalence of severe breathlessness is likely to be the same in the group of patients who refused to be interviewed as in the rest of the sample?
Selection AYes
Selection BNo

 

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