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Trial Design: Pain Sections
Author Bio
Introduction
Placebo Effects
Single Dose Trials
Repeated Dose Trials
Explanatory Versus Pragmatic
Currently selected section: Dose-Response
Parallel Group Versus Crossover
Conclusion
 

 

Chapter 1: Clinical Trials of Pain Treatment: Dose-Response; Relative Potency; Combinations

 
         

Do you favor the proposed pilot study?

You answered:

NoI would not favor the proposed pilot study.


CORRECT

Pilot studies are often helpful, but the placebo effect is so variable in symptom studies that an open-label study might be misleading. One should insist on a double-blind placebo-controlled trial.

 

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