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Would the use of a crossover design be likely
to offer advantages over a parallel group design in comparing postoperative pain
to placebo?
You
answered:
Yes.
Yes
or No May Be Correct
Postoperative pain is a rapidly
evolving condition. In oral surgery and other minor procedures,
pain rapidly decreases after the first 6 hours and treatment
comparisons after the first dose have yielded little (Stewart,
1991). James
et al. (1985) showed that crossover designs may be feasible
after major thoracic and abdominal procedures that cause
several days of severe pain, but almost all recent postoperative
pain studies have used parallel group design.
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