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Would the use of a crossover design be likely
to offer advantages over a parallel group design in comparing postoperative pain
to placebo?
You
answered:
No.
Yes
or No May Be Correct
Postoperative
pain is a rapidly evolving condition. In oral surgery and
other minor procedures, pain rapidly decreases after the
first 6 hours and treatment comparisons after the first
dose have yielded little (Stewart,
1991). James
et al. (1985) showed that crossover designs may be feasible
after major thoracic and abdominal procedures that cause
several days of severe pain, but almost all recent postoperative
pain studies have used parallel group design.
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