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A Study of Insomnia and Sleep Loss
Author Bio
Part I
Part II
Using a Stress Framework
Protocol Design
Currently selected section: SNS Activation
Sleep Misperception and Loss
Insomnia and Performance Testing
Insomnia and Emotional Arousal
Yoked Control Design
Effects of Sleep Loss
Insomnia and Somatic Symptoms
Conclusion
 
 
 
 


Chapter 15: Challenges to the Study of Insomnia and Sleep Loss: Measurement and Evaluation of SNS Activation
        

Another variable coming to the forefront as an indicator of autonomic nervous system (ANS) function is heart rate variability. The ANS regulation of the heart rate is known in significant detail and high performance computer analysis of the electrocardiogram (ECG) allows quantification of the modulations in heart rate that are a product of ANS regulation. Heart rate (or beat-to-beat interval), even in the absence of external perturbations or challenges is not constant but rather oscillates (or varies) around a mean value. Rhythmic fluctuations in the sinus rate over time constitute heart rate variability.

A typical HR time series and power spectrum shows that most of the ECG power is concentrated in two frequency bands, a low (0.03 - 0.15 Hz) and a high (usually 0.15 - 0.5 Hz) frequency band. Their relationship to one another is considered to reflect a relative balance of SNS versus parasympathetic (PSNS) activity as depicted in the figures below:

Figure 3.3.4: Typical Heart Rate Time Series and Corresponding Heart Rate Power Spectrum for Supine, Healthy Adult
Graphic depiction of typical heart rate time series, described in text.

Source: Akselrod S. Component of heart rate variability. In: Malik M, Camm AJ eds. Heart Rate Variability. Armonk, NY. Futura Publishing Company, Inc. 1995: 147-163. Reprinted by permission of Blackwell Science, Inc and Solange Akselrod.

Figure 3.3.5: Heart Rate Time Series and Power Spectrum for Same Adult Upon Standing
Graphic depiction of heart rate time series, described in text.

Source: Akselrod S. Component of heart rate variability. In: Malik M, Camm AJ eds. Heart Rate Variability. Armonk, NY. Futura Publishing Company, Inc. 1995: 147-163. Reprinted by permission of Blackwell Science, Inc and Solange Akselrod.

 

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