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Chemotherapy-Related Nausea & Vomiting
Author Bio
Introduction
What Causes Nausea & Vomiting?
Automatic Nervous System
Chemotherapy Induced NV
NV Control
Issues in Research Design
Currently selected section: Case Study 1
Case Study 2
Summary


Chapter 11: Chemotherapy-Related Nausea & Vomiting: Case Study 1
        

Systematic desensitization, or counterconditioning, is a well-developed, standardized behavioral technique that has been found to be effective against anticipatory nausea associated with cancer chemotherapy. The key elements of SD (illustrated in the diagram below) can be taught to patients in about 20 minutes.

Systematic desensitization: Construct hierarchy of events related to original stimulus which elicits the maladaptive response for each patient. 1. Driving to clinic, 2. Entering treatment room, 3. Seeing clinic nurse. Train patient to associate alternative responses (e.g., deep muscle relaxation) with these events.

The next logical step in this research was to determine both of the major component parts (i.e. relaxation and creating a cognitive hierarchy) of the systematic desensitization procedure which were required. Such research would have both practical and theoretical aims.

  • The practical aim was to see if the treatment of anticipatory side effects could be made more cost-effective by the use of relaxation as opposed to requiring professional time for doing systematic desensitization. Teaching relaxation alone requires less professional time and expertise than desensitization. If the relaxation alone was found to be as effective as the desensitization, then the possibility of competent treatment by a wide variety of professions and persons of varying backgrounds would be enhanced.

  • The theoretical aim involved the opportunity, provided by the study, to do a component analysis of whether the hierarchy and cognitive involvement present in the systematic desensitization resulted in greater efficacy than relaxation alone. If relaxation alone was found as effective as the desensitization, then a reduction in general arousal or some nonspecific effect on the gastric system might be the active component. On the other hand, superiority of desensitization would provide support for the involvement of cognitive processes in the development of anticipatory side effects.


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